13 Things That Don't Make Sense
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''13 Things That Don't Make Sense'' is a non-fiction book by the British writer Michael Brooks, published in both the UK and the US during 2008. The British subtitle is "The Most ''Intriguing'' Scientific Mysteries of Our Time" while the American is "The Most ''Baffling''..." (see image). Based on an article Brooks wrote for ''
New Scientist ''New Scientist'' is a magazine covering all aspects of science and technology. Based in London, it publishes weekly English-language editions in the United Kingdom, the United States and Australia. An editorially separate organisation publishe ...
'' in March 2005,Brooks, Michael
13 Things That Don't Make Sense
March 2005, space.newscientist.com
the book, aimed at the general reader rather than the science community, contains discussion and description of a number of unresolved issues in science. It is a literary effort to discuss some of the inexplicable anomalies that after centuries science still cannot completely comprehend.Brooks, Michael, 13 Things That Don't Make Sense, August 2008, Random House Inc.,


Chapter 1

The Missing Universe. This chapter deals with
astronomy Astronomy () is a natural science that studies astronomical object, celestial objects and phenomena. It uses mathematics, physics, and chemistry in order to explain their origin and chronology of the Universe, evolution. Objects of interest ...
and
theoretical physics Theoretical physics is a branch of physics that employs mathematical models and abstractions of physical objects and systems to rationalize, explain and predict natural phenomena. This is in contrast to experimental physics, which uses experim ...
and the
ultimate fate of the universe The ultimate fate of the universe is a topic in physical cosmology, whose theoretical restrictions allow possible scenarios for the evolution and ultimate fate of the universe to be described and evaluated. Based on available observational ev ...
, in particular the search for understanding of
dark matter Dark matter is a hypothetical form of matter thought to account for approximately 85% of the matter in the universe. Dark matter is called "dark" because it does not appear to interact with the electromagnetic field, which means it does not ab ...
and
dark energy In physical cosmology and astronomy, dark energy is an unknown form of energy that affects the universe on the largest scales. The first observational evidence for its existence came from measurements of supernovas, which showed that the univer ...
and includes discussion of: * The work of astronomers
Vesto Slipher Vesto Melvin Slipher (; November 11, 1875 – November 8, 1969) was an American astronomer who performed the first measurements of radial velocities for galaxies. He was the first to discover that distant galaxies are redshifted, thus providing th ...
and then
Edwin Hubble Edwin Powell Hubble (November 20, 1889 – September 28, 1953) was an Americans, American astronomer. He played a crucial role in establishing the fields of extragalactic astronomy and observational cosmology. Hubble proved that many objects ...
in demonstrating the universe is expanding; *
Vera Rubin Vera Florence Cooper Rubin (; July 23, 1928 – December 25, 2016) was an American astronomer who pioneered work on galaxy rotation rates. She uncovered the discrepancy between the predicted and observed angular motion of galaxies by studyi ...
's investigation of
galaxy rotation curve The rotation curve of a disc galaxy (also called a velocity curve) is a plot of the orbital speeds of visible stars or gas in that galaxy versus their radial distance from that galaxy's centre. It is typically rendered graphically as a plot, and ...
s that suggest something other than gravity is preventing galaxies from spinning apart, which led to the revival of unobserved "dark matter" theory; * Experimental efforts to discover dark matter, including the search for the hypothetical
neutralino In supersymmetry, the neutralino is a hypothetical particle. In the Minimal Supersymmetric Standard Model (MSSM), a popular model of realization of supersymmetry at a low energy, there are four neutralinos that are fermions and are electrically ...
and other
weakly interacting massive particles Weakly interacting massive particles (WIMPs) are hypothetical particles that are one of the proposed candidates for dark matter. There exists no formal definition of a WIMP, but broadly, a WIMP is a new elementary particle which interacts via gra ...
); * The study of
supernova A supernova is a powerful and luminous explosion of a star. It has the plural form supernovae or supernovas, and is abbreviated SN or SNe. This transient astronomical event occurs during the last evolutionary stages of a massive star or when ...
e at
Lawrence Berkeley National Laboratory Lawrence Berkeley National Laboratory (LBNL), commonly referred to as the Berkeley Lab, is a United States Department of Energy National Labs, United States national laboratory that is owned by, and conducts scientific research on behalf of, t ...
and
Harvard University Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher le ...
(under
Robert Kirshner Robert P. Kirshner (born August 15, 1949) is an American astronomer, Chief Program Officer for Science for the Gordon and Betty Moore Foundation, and the Clownes Research Professor of Science at Harvard University. Kirshner has worked in several ...
) that point to an
accelerating universe Observations show that the expansion of the universe is accelerating, such that the velocity at which a distant galaxy recedes from the observer is continuously increasing with time. The accelerated expansion of the universe was discovered during ...
powered by "dark energy" possibly
vacuum energy Vacuum energy is an underlying background energy that exists in space throughout the entire Universe. The vacuum energy is a special case of zero-point energy that relates to the quantum vacuum. The effects of vacuum energy can be experimental ...
; * The assertion that the proposed
modified Newtonian dynamics Modified Newtonian dynamics (MOND) is a hypothesis that proposes a modification of Newton's law of universal gravitation to account for observed properties of galaxies. It is an alternative to the hypothesis of dark matter in terms of explaining ...
hypothesis and the accelerating universe disproves the dark matter theory.


Chapter 2

The
Pioneer Anomaly The Pioneer anomaly, or Pioneer effect, was the observed deviation from predicted accelerations of the ''Pioneer 10'' and ''Pioneer 11'' spacecraft after they passed about on their trajectories out of the Solar System. The apparent anomaly was ...
. This discusses the ''
Pioneer 10 ''Pioneer 10'' (originally designated Pioneer F) is an American space probe, launched in 1972 and weighing , that completed the first mission to the planet Jupiter. Thereafter, ''Pioneer 10'' became the first of five artificial objects to ach ...
'' and ''
Pioneer 11 ''Pioneer 11'' (also known as ''Pioneer G'') is a robotic space probe launched by NASA on April 5, 1973, to study the asteroid belt, the environment around Jupiter and Saturn, solar winds, and cosmic rays. It was the first probe to encounter ...
'' space probes, which appear to be veering off course and drifting towards the sun. At the time of writing of the book there was a growing speculation as to whether this phenomenon could be explained by a yet-undetermined fault in the rockets' systems or whether this was an unidentified effect of gravity. The lead investigator into the progress of the rockets is physicist
Slava Turyshev Slava G. Turyshev (russian: Слава Турышев) is a Russian physicist now working in the US at the NASA Jet Propulsion Laboratory (JPL). He is known for his investigations of the Pioneer anomaly, affecting Pioneer 10 and Pioneer 11 spacec ...
of the
NASA The National Aeronautics and Space Administration (NASA ) is an independent agency of the US federal government responsible for the civil space program, aeronautics research, and space research. NASA was established in 1958, succeeding t ...
Jet Propulsion Laboratory The Jet Propulsion Laboratory (JPL) is a federally funded research and development center and NASA field center in the City of La Cañada Flintridge, California, United States. Founded in the 1930s by Caltech researchers, JPL is owned by NASA an ...
in California who is analysing the data of the rockets' launch and progress and "reflying" the missions as computer simulations to try to find a solution to the mystery. However, in 2012, after the book was published, Turyshev was able to give an
explanation An explanation is a set of Statement (logic), statements usually constructed to description, describe a set of facts which clarifies the causality, causes, wiktionary:context, context, and Logical consequence, consequences of those facts. It may ...
to the Pioneer Anomaly.


Chapter 3

Varying Constants. This chapter discusses the reliability of some
physical constant A physical constant, sometimes fundamental physical constant or universal constant, is a physical quantity that is generally believed to be both universal in nature and have constant value in time. It is contrasted with a mathematical constant, ...
s, quantities or values that are held to be always fixed. One of these, the
Fine-structure constant In physics, the fine-structure constant, also known as the Sommerfeld constant, commonly denoted by (the Greek letter ''alpha''), is a fundamental physical constant which quantifies the strength of the electromagnetic interaction between ele ...
, which calculates the behaviour and amount of energy transmitted in subatomic interactions from light reflection and refraction to nuclear fusion, has been called into question by physicist John Webb of the
University of New South Wales The University of New South Wales (UNSW), also known as UNSW Sydney, is a public research university based in Sydney, New South Wales, Australia. It is one of the founding members of Group of Eight, a coalition of Australian research-intensive ...
who may have identified differences in the behaviour of light from
quasar A quasar is an extremely Luminosity, luminous active galactic nucleus (AGN). It is pronounced , and sometimes known as a quasi-stellar object, abbreviated QSO. This emission from a galaxy nucleus is powered by a supermassive black hole with a m ...
s and light sources today. According to Webb's observations quasar light appears to refract different shades of colour from light waves emitted today. Brooks also discusses the
Oklo Oklo is a region near the town of Franceville, in the Haut-Ogooué province of the Central African country of Gabon. Several natural nuclear fission reactors were discovered in the uranium mines in the region in 1972. History Gabon was a French ...
natural nuclear fission reactor A natural nuclear fission reactor is a uranium deposit where self-sustaining nuclear chain reactions occur. The conditions under which a natural nuclear reactor could exist had been predicted in 1956 by Japanese American chemist Paul Kuroda. Th ...
, in which the natural conditions in caves in
Gabon Gabon (; ; snq, Ngabu), officially the Gabonese Republic (french: République gabonaise), is a country on the west coast of Central Africa. Located on the equator, it is bordered by Equatorial Guinea to the northwest, Cameroon to the north ...
2 billion years ago caused the
uranium Uranium is a chemical element with the symbol U and atomic number 92. It is a silvery-grey metal in the actinide series of the periodic table. A uranium atom has 92 protons and 92 electrons, of which 6 are valence electrons. Uranium is weak ...
there to react. It may be that the amount of energy released was different from today. Both sets of data are subject to ongoing investigation and debate but, Brooks suggests, may indicate that the behaviour of matter and energy can vary radically and essentially as the conditions of the universe changes through time.


Chapter 4

Cold Fusion Cold fusion is a hypothesized type of nuclear reaction that would occur at, or near, room temperature. It would contrast starkly with the "hot" fusion that is known to take place naturally within stars and artificially in hydrogen bombs and p ...
. A review of efforts to create nuclear energy at room temperature using hydrogen that is embedded in a metal crystal lattice. Theoretically, this should not happen, because nuclear fusion requires a huge
activation energy In chemistry and physics, activation energy is the minimum amount of energy that must be provided for compounds to result in a chemical reaction. The activation energy (''E''a) of a reaction is measured in joules per mole (J/mol), kilojoules pe ...
to get it started. The effect was first reported by chemists
Martin Fleischmann Martin Fleischmann FRS (29 March 1927 â€“ 3 August 2012) was a British chemist who worked in electrochemistry. By Associated Press. Premature announcement of his cold fusion research with Stanley Pons, regarding excess heat in heavy wa ...
and
Stanley Pons Bobby Stanley Pons (born August 23, 1943) is an American electrochemist known for his work with Martin Fleischmann on cold fusion in the 1980s and 1990s. Early life Pons was born in Valdese, North Carolina. He attended Valdese High School, then ...
in 1989, but attempts to reproduce it over the ensuing months were mostly unsuccessful. Cold fusion research was discredited, and articles on the subject became difficult to publish. But according to the book, a scattering of scientists around the world continue to report positive results, with multiple, independent verifications.


Chapter 5

Life Life is a quality that distinguishes matter that has biological processes, such as signaling and self-sustaining processes, from that which does not, and is defined by the capacity for growth, reaction to stimuli, metabolism, energ ...
. This chapter describes efforts to define life and how it emerged from inanimate matter (
abiogenesis In biology, abiogenesis (from a- 'not' + Greek bios 'life' + genesis 'origin') or the origin of life is the natural process by which life has arisen from non-living matter, such as simple organic compounds. The prevailing scientific hypothes ...
) and even recreate
artificial life Artificial life (often abbreviated ALife or A-Life) is a field of study wherein researchers examine systems related to natural life, its processes, and its evolution, through the use of simulations with computer models, robotics, and biochemistry ...
including: the
Miller–Urey experiment The Miller–Urey experiment (or Miller experiment) is a famous chemistry experiment that simulated the conditions thought at the time (1952) to be present in the atmosphere of the early, prebiotic Earth, in order to test the hypothesis of the ...
by chemists
Stanley Miller Stanley Lloyd Miller (March 7, 1930 – May 20, 2007) was an American chemist who made landmark experiments in the origin of life by demonstrating that a wide range of vital organic compounds can be synthesized by fairly simple chemical processe ...
and
Harold Urey Harold Clayton Urey ( ; April 29, 1893 – January 5, 1981) was an American physical chemist whose pioneering work on isotopes earned him the Nobel Prize in Chemistry in 1934 for the discovery of deuterium. He played a significant role in the d ...
at the
University of Chicago The University of Chicago (UChicago, Chicago, U of C, or UChi) is a private research university in Chicago, Illinois. Its main campus is located in Chicago's Hyde Park neighborhood. The University of Chicago is consistently ranked among the b ...
in 1953 to spark life into a mixture of chemicals by using an electrical charge; Steen Rasmussen's work at the
Los Alamos National Laboratory Los Alamos National Laboratory (often shortened as Los Alamos and LANL) is one of the sixteen research and development laboratories of the United States Department of Energy (DOE), located a short distance northwest of Santa Fe, New Mexico, ...
to implant primitive DNA,
peptide nucleic acid Peptide nucleic acid (PNA) is an artificially synthesized polymer similar to DNA or RNA. Synthetic peptide nucleic acid oligomers have been used in recent years in molecular biology procedures, diagnostic assays, and antisense therapies. Due to ...
, into soap molecules and heat them up; and the work of the
Institute for Complex Adaptive Matter The Institute for Complex Adaptive Matter (ICAM) is an international multicampus collective of scientists studying emergent phenomena in biology, chemistry and physics and in wider context. ICAM was founded in December 1998 at the Los Alamos Nation ...
at the
University of California The University of California (UC) is a public land-grant research university system in the U.S. state of California. The system is composed of the campuses at Berkeley, Davis, Irvine, Los Angeles, Merced, Riverside, San Diego, San Francisco, ...
.


Chapter 6

Viking. A discussion of the experiments by engineer
Gilbert Levin Gilbert Victor Levin (April 23, 1924 – July 26, 2021) was an American engineer, the founder of Biospherics and the principal investigator of the ''Viking'' mission Labeled Release experiment. He was born in Baltimore, Maryland. In 1997, Levin ...
to search for life on
Mars Mars is the fourth planet from the Sun and the second-smallest planet in the Solar System, only being larger than Mercury (planet), Mercury. In the English language, Mars is named for the Mars (mythology), Roman god of war. Mars is a terr ...
in the 1970s as part of the
Viking program The ''Viking'' program consisted of a pair of identical American space probes, ''Viking 1'' and ''Viking 2'', which landed on Mars in 1976. Each spacecraft was composed of two main parts: an orbiter designed to photograph the surface of Mars f ...
. Levin's Labeled Release experiment appeared to conclusively show that life does exist on Mars, but as his results were not supported by the other three
Viking biological experiments In 1976 two identical Viking program landers each carried four types of biological experiments to the surface of Mars. The first successful Mars landers, ''Viking 1'' and ''Viking 2'', then carried out experiments to look for biosignatures of mic ...
, they were called into question and eventually not accepted by
NASA The National Aeronautics and Space Administration (NASA ) is an independent agency of the US federal government responsible for the civil space program, aeronautics research, and space research. NASA was established in 1958, succeeding t ...
, which instead hypothesized that the gases observed being generated may not have been a product of living metabolism but of a chemical reaction of
hydrogen peroxide Hydrogen peroxide is a chemical compound with the formula . In its pure form, it is a very pale blue liquid that is slightly more viscous than water. It is used as an oxidizer, bleaching agent, and antiseptic, usually as a dilute solution (3%†...
. Brooks goes into detail on some of Levin's other experiments and also describes how NASA's subsequent missions to Mars have focused on the geology and climate of the planet rather than looking for life on the planet. (Several missions are searching for water and geological conditions which could support
life on Mars The possibility of life on Mars is a subject of interest in astrobiology due to the planet's proximity and similarities to Earth. To date, no proof of past or present life has been found on Mars. Cumulative evidence suggests that during the ...
currently or in the past.)


Chapter 7

The
Wow! Signal The Wow! signal was a strong narrowband radio signal detected on August 15, 1977, by Ohio State University's Big Ear radio telescope in the United States, then used to support the search for extraterrestrial intelligence. The signal appeared ...
. Brooks discusses whether or not the signal spotted by astronomer Jerry R. Ehman at the ''
Big Ear The Ohio State University Radio Observatory was a Kraus-type (after its inventor John D. Kraus) radio telescope located on the grounds of the Perkins Observatory at Ohio Wesleyan University in Delaware, Ohio from 1963 to 1998. Known as Big Ear, th ...
''
radio telescope A radio telescope is a specialized antenna and radio receiver used to detect radio waves from astronomical radio sources in the sky. Radio telescopes are the main observing instrument used in radio astronomy, which studies the radio frequency ...
of
Ohio State University The Ohio State University, commonly called Ohio State or OSU, is a public land-grant research university in Columbus, Ohio. A member of the University System of Ohio, it has been ranked by major institutional rankings among the best publ ...
in 1977 was a genuine indication of intelligent life in outer space. This was a remarkably clear signal and ''Big Ear'' was the largest and longest running
SETI The search for extraterrestrial intelligence (SETI) is a collective term for scientific searches for intelligent extraterrestrial life, for example, monitoring electromagnetic radiation for signs of transmissions from civilizations on other p ...
(Search for Extra-Terrestrial Intelligence) radio-telescope project in the world. Brooks goes on to discuss the abandonment of
NASA The National Aeronautics and Space Administration (NASA ) is an independent agency of the US federal government responsible for the civil space program, aeronautics research, and space research. NASA was established in 1958, succeeding t ...
's Microwave Observing Program after government funding was stopped by the efforts of senator
Richard Bryan Richard Hudson Bryan (born July 16, 1937) is an American attorney and politician A politician is a person active in party politics, or a person holding or seeking an elected office in government. Politicians propose, support, reject and cr ...
of
Nevada Nevada ( ; ) is a U.S. state, state in the Western United States, Western region of the United States. It is bordered by Oregon to the northwest, Idaho to the northeast, California to the west, Arizona to the southeast, and Utah to the east. N ...
. There is no public funding for similar observations today while the
SETI Institute The SETI Institute is a not-for-profit research organization incorporated in 1984 whose mission is to explore, understand, and explain the origin and nature of life in the universe, and to use this knowledge to inspire and guide present and futu ...
, which continues NASA's work, is funded by private donation, as are a number of other initiatives.


Chapter 8

A Giant Virus. Brooks describes the huge and highly resistant
Mimivirus ''Mimivirus'' is a genus of giant viruses, in the family ''Mimiviridae''. Amoeba serve as their natural hosts. This genus contains a single identified species named ''Acanthamoeba polyphaga mimivirus'' (APMV). It also refers to a group of phylo ...
found in
Bradford Bradford is a city and the administrative centre of the City of Bradford district in West Yorkshire, England. The city is in the Pennines' eastern foothills on the banks of the Bradford Beck. Bradford had a population of 349,561 at the 2011 ...
, England in 1992 and whether this challenges the traditional view of
virus A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea. Since Dmitri Ivanovsky's 1 ...
es being inanimate chemicals rather than living things. Mimivirus is not only much larger than most viruses but it also has a much more complex genetic structure. The discovery of Mimivirus has given weight to the theories of microbiologist Philip Bell and others that viral infection was indeed the reason for the emergence from primitive life forms of complex cell structures based on a
cell nucleus The cell nucleus (pl. nuclei; from Latin or , meaning ''kernel'' or ''seed'') is a membrane-bound organelle found in eukaryotic cells. Eukaryotic cells usually have a single nucleus, but a few cell types, such as mammalian red blood cells, h ...
. (See viral eukaryogenesis.) Study of the behaviour and structure of viruses is ongoing.


Chapter 9

Death Death is the irreversible cessation of all biological functions that sustain an organism. For organisms with a brain, death can also be defined as the irreversible cessation of functioning of the whole brain, including brainstem, and brain ...
. Beginning with the example of
Blanding's turtle Blanding's turtle (''Emydoidea blandingii'') is a semi-aquatic turtle of the family Emydidae. This species is native to central and eastern parts of Canada and the United States. It is considered to be an endangered species throughout much of i ...
and certain species of fish, amphibians and reptiles that do not age as they grow older, Brooks discusses theories and research into the
evolution of ageing Enquiry into the evolution of ageing, or aging, aims to explain why a detrimental process such as ageing would evolve, and why there is so much variability in the lifespans of organisms. The classical theories of evolution (mutation accumulation, ...
. These include the studies of
Peter Medawar Sir Peter Brian Medawar (; 28 February 1915 – 2 October 1987) was a Brazilian-British biologist and writer, whose works on graft rejection and the discovery of acquired immune tolerance have been fundamental to the medical practice of tissue ...
and George C. Williams in the 1950s and Thomas Johnson, David Friedman and
Cynthia Kenyon Cynthia Jane Kenyon (born February 21, 1954) is an American molecular biologist and biogerontologist known for her genetic dissection of aging in a widely used model organism, the roundworm ''Caenorhabditis elegans''. She is the vice president of ...
in the 1980s claiming that
ageing Ageing ( BE) or aging ( AE) is the process of becoming older. The term refers mainly to humans, many other animals, and fungi, whereas for example, bacteria, perennial plants and some simple animals are potentially biologically immortal. In ...
is a genetic process that has evolved as organism select genes that help them to grow and reproduce over ones that help them to thrive in later life. Brooks also talks about
Leonard Hayflick Leonard Hayflick (born 20 May 1928) is a Professor of Anatomy at the UCSF School of Medicine, and was Professor of Medical Microbiology at Stanford University School of Medicine. He is a past president of the Gerontological Society of America and ...
, as well as others, who have observed that cells in culture will at a fixed point in time stop reproducing and die as their DNA eventually becomes corrupted by continuous division, a mechanical process at cell level rather than part of a creature's genetic code.


Chapter 10

Sex Sex is the trait that determines whether a sexually reproducing animal or plant produces male or female gametes. Male plants and animals produce smaller mobile gametes (spermatozoa, sperm, pollen), while females produce larger ones ( ova, of ...
. This chapter is a discussion of theories of the
evolution of sexual reproduction Sexual reproduction is an adaptive feature which is common to almost all multicellular organisms and various unicellular organisms, with some organisms being incapable of asexual reproduction. Currently the adaptive advantage of sexual reprodu ...
. The provided explanation is that although
asexual reproduction Asexual reproduction is a type of reproduction that does not involve the fusion of gametes or change in the number of chromosomes. The offspring that arise by asexual reproduction from either unicellular or multicellular organisms inherit the fu ...
is much easier and more efficient for an organism it is less common than sexual reproduction because having two parents allows species to adapt and evolve more easily to survive in changing environments. Brooks discusses efforts to prove this by laboratory experiment and goes on to discuss alternative theories including the work of Joan Roughgarden of
Stanford University Stanford University, officially Leland Stanford Junior University, is a private research university in Stanford, California. The campus occupies , among the largest in the United States, and enrolls over 17,000 students. Stanford is consider ...
who proposes that sexual reproduction, rather than being driven by
Charles Darwin Charles Robert Darwin ( ; 12 February 1809 â€“ 19 April 1882) was an English naturalist, geologist, and biologist, widely known for his contributions to evolutionary biology. His proposition that all species of life have descended fr ...
's
sexual selection Sexual selection is a mode of natural selection in which members of one biological sex mate choice, choose mates of the other sex to mating, mate with (intersexual selection), and compete with members of the same sex for access to members of t ...
in individuals, is a mechanism for the survival of social groupings, which most higher species depend on for survival.


Chapter 11

Free Will Free will is the capacity of agents to choose between different possible courses of action unimpeded. Free will is closely linked to the concepts of moral responsibility, praise, culpability, sin, and other judgements which apply only to actio ...
. Discusses the experimental investigations into the
Neuroscience of free will Neuroscience of free will, a part of neurophilosophy, is the study of topics related to free will ( volition and sense of agency) using neuroscience, and the analysis of how findings from such studies may impact the free will debate. As it has b ...
by
Benjamin Libet Benjamin Libet (; April 12, 1916 – July 23, 2007) was an American neuroscientist who was a pioneer in the field of human consciousness. Libet was a researcher in the physiology department of the University of California, San Francisco. In 2003, ...
of the
University of California, San Francisco The University of California, San Francisco (UCSF) is a public land-grant research university in San Francisco, California. It is part of the University of California system and is dedicated entirely to health science and life science. It cond ...
and others, which show that the brain seems to commit to certain decisions before the person becomes aware of having made them and discusses the implications of these findings on our conception of free will.


Chapter 12

The
Placebo Effect A placebo ( ) is a substance or treatment which is designed to have no therapeutic value. Common placebos include inert tablets (like sugar pills), inert injections (like Saline (medicine), saline), sham surgery, and other procedures. In general ...
. This is a discussion of the role of the placebo in modern medicine, including examples such as
Diazepam Diazepam, first marketed as Valium, is a medicine of the benzodiazepine family that acts as an anxiolytic. It is commonly used to treat a range of conditions, including anxiety, seizures, alcohol withdrawal syndrome, muscle spasms, insomnia, a ...
, which, Brooks claims, in some situations appears to work only if the patient knows they are taking it. Brooks describes research into prescription behaviour which appears to show that use of placebos is commonplace. He describes the paper by Asbjørn Hrobjartsson and
Peter C. Gøtzsche Peter Christian Gøtzsche (born 26 November 1949) is a Danish physician, medical researcher, and former leader of the Nordic Cochrane Center at Rigshospitalet in Copenhagen, Denmark. He is a co-founder of the Cochrane Collaboration and has writ ...
in the
New England Journal of Medicine ''The New England Journal of Medicine'' (''NEJM'') is a weekly medical journal published by the Massachusetts Medical Society. It is among the most prestigious peer-reviewed medical journals as well as the oldest continuously published one. Hist ...
that challenges use of placebos entirely, and the work of others towards an understanding of the mechanism of the effect.


Chapter 13

Homeopathy Homeopathy or homoeopathy is a pseudoscientific system of alternative medicine. It was conceived in 1796 by the German physician Samuel Hahnemann. Its practitioners, called homeopaths, believe that a substance that causes symptoms of a dis ...
. Brooks discusses the work of researcher Madeleine Ennis involving a homeopathic solution which once contained
histamine Histamine is an organic nitrogenous compound involved in local immune responses, as well as regulating physiological functions in the gut and acting as a neurotransmitter for the brain, spinal cord, and uterus. Since histamine was discovered in ...
but was diluted to the point where no histamine remained. Brooks conjectures that the results might be explained by some previously unknown property of water. Brooks supports the investigation of documented anomalies even though he is critical of the practice of homeopathy in general, as are many of the scientists he cites, such as Martin Chaplin of
South Bank University London South Bank University (LSBU) is a public university in Elephant and Castle, London. It is based in the London Borough of Southwark, near the South Bank of the River Thames, from which it takes its name. Founded in 1892 as the Borough Po ...
.


References


Further reading

Chapter 1 * * * * *


External links

*
''13 more things that don't make sense''
at
New Scientist ''New Scientist'' is a magazine covering all aspects of science and technology. Based in London, it publishes weekly English-language editions in the United Kingdom, the United States and Australia. An editorially separate organisation publishe ...
* {{cite web, title=TEDxYouth@Manchester 2011 - Michael Brooks - The Things That Don't Make Sense, date=November 8, 2011, publisher=TEDxYouth, website=YouTube, url=https://www.youtube.com/watch?v=DdFUG0sQjus 2008 non-fiction books Popular science books Profile Books books Cold fusion Dark matter Free will Homeopathy Unexplained phenomena